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911. PIK3C3
Crystal structure of human PIK3C3 in complex with 3-[4-(4-Morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol (Compound 15E)
PDB: 3LS8 (2010-02-12)
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899. DHX9
DEAH (Asp-Glu-Ala-His box polypeptide 9 isoform 1
PDB: 3LLM (2010-01-31)
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877. NUDT16L1
Human NUDT16-like protein 1 (Syndesmos)
PDB: 3KVH (2009-11-30)
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871. TNKS2
Human Tankyrase-2, catalytic PARP domain in complex with inhibitor XAV939
PDB: 3KR8 (2009-11-18)
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870. TNKS2
Human Tankyrase-2, catalytic PARP domain
PDB: 3KR7 (2009-11-18)
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862. PARP15
Human poly(ADP-ribose) polymerase 15, macro domain 2 in complex with adenosine-5-diphosphoribose
PDB: 3KH6 (2009-10-30)
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867. PTGDS
Human prostaglandin-H2 D-isomerase
PDB: 2WWP (2009-10-26)
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856. PARP2
Human poly(ADP-ribose) polymerase 2 in complex with ABT-888
PDB: 3KJD (2009-10-22)
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855. PARP2
Human poly(ADP-ribose) polymerase 2
PDB: 3KCZ (2009-10-22)
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854. PIK3C2GA
The phox homology (PX) domain of human phosphoinositide-3-kinase-C2-gamma
PDB: 2WWE (2009-10-22)
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849. ACOT4
Human Acyl-Coenzyme A Thioesterase 4
PDB: 3K2I (2009-09-30)
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838. DDX53
Human DEAD-box RNA helicase DDX53, DEAD-box domain in complex with AMP
PDB: 3IUY (2009-08-31)
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835. HSPA5
70kDa heat shock protein 5 (BiP) ATPase domain in complex with ADP
PDB: 3IUC (2009-08-31)
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826. SNX7
Human Sorting Nexin 7, phox homology (px) domain
PDB: 3IQ2 (2009-08-19)
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823. PIK3C3
Phosphoinositide-3-kinase, class 3
PDB: 3IHY (2009-07-31)
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818. CTPS2
Human CTPS2 in complex with ADP
PDB: 3IHL (2009-07-30)
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817. GPT2
Human alanine aminotransferase 2 in complex with PLP
PDB: 3IHJ (2009-07-30)
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812. UMPS
Human OPRTASE domain of Uridine 5
PDB: 2WNS (2009-07-19)
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804. LASP1
Human SH3 domain of LIM and SH3 domain protein 1
PDB: 3I35 (2009-06-30)
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803. HSPA2
Human heat shock 70kDa protein 2 (HSPA2)
PDB: 3I33 (2009-06-30)
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792. FLT1
Kinase domain of human VEGFR1
PDB: 3HNG (2009-05-31)
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783. PARP10
Human Poly (ADP-ribose) Polymerase 10, catalytic domain in complex with an inhibitor 3-Aminobenzamide
PDB: 3HKV (2009-05-26)
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779. TBSAHA
S-adenosyl homocysteine hydrolase (SAHH) from Trypanosoma brucei (Pathogen)
PDB: 3H9U (2009-04-30)
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775. NUDT6A
Human nudix (nucleoside diphosphate linked moiety X)-type motif 6, C-terminal domain
PDB: 3H95 (2009-04-30)
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763. RRM1
Human Ribonucleotide Reductase R1 subunit (RRM1) in complex with dATP and Magnesium
PDB: 2WGH (2009-04-17)
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761. KIAA0828
Human S-adenosyl homocysteine hydrolase-like 2 protein (AHCYL2)
PDB: 3GVP (2009-03-31)
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751. BPNT1
Human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1) in complex with AMP, Mg and PO4
PDB: 2WEF (2009-03-30)
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746. PARP14
Human Poly (ADP-ribose) Polymerase 14, catalytic domain in complex with an inhibitor 3-Aminobenzamide
PDB: 3GOY (2009-03-20)
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741. NUDT18
Human NUDT18, NUDIX domain
PDB: 3GG6 (2009-02-27)
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735. PARP15
Human Poly(ADP-ribose) polymerase 15, catalytic fragment in complex with an inhibitor PJ34
PDB: 3GEY (2009-02-26)
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734. HSPA1L
Human heat shock 70 kDa protein 1-like, ATP-ase domain in complex with ADP
PDB: 3GDQ (2009-02-24)
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728. LMSAH
Leishmania major S-adenosylhomocysteine hydrolase
PDB: 3G1U (2009-01-30)
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723. DDX19
Human dead-box RNA helicase DDX19, in complex with an ATP-analogue and RNA
PDB: 3G0H (2009-01-22)
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720. NUDT6
Human NUDT6, N-terminal domain
PDB: 3FXT (2009-01-21)
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717. SNX17
Human sorting nexin-17, PX domain
PDB: 3FOG (2008-12-30)
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716. TBCTPS
Trypanosoma brucei CTP synthetase - glutaminase domain in complex with acivicin
PDB: 2W7T (2008-12-30)
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714. ACOT11
Human START domain of Acyl-coenzyme A thioesterase 11
PDB: 3FO5 (2008-12-27)
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693. DCTD
Human dCMP deaminase
PDB: 2W4L (2008-11-28)
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691. DDX5
Human DEAD box RNA helicase DDX5 (p68)
PDB: 3FE2 (2008-11-27)
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690. HSPA6
Human heat shock 70kDa protein 6 (HSP70B) , ATPase domain in complex with ADP
PDB: 3FE1 (2008-11-27)
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676. NUMBL
Human NUMB-like protein, phosphotyrosine interaction domain
PDB: 3F0W (2008-10-27)
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673. DDX19
Human DEAD-box RNA-helicase DDX19 in complex with ADP
PDB: 3EWS (2008-10-16)
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671. SKIL
Human SKI-like
PDB: 3EQ5 (2008-09-30)
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663. CTPS2
Human CTP synthetase 2 - glutaminase domain in complex with 5-OXO-L-NORLEUCINE
PDB: 2V4U (2008-09-29)
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659. GFPT1
Human Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1)
PDB: 2V4M (2008-09-26)
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657. PCYT2
Human CTP:Phosphoethanolamine Cytidylyltransferase
PDB: 3ELB (2008-09-22)
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653. FLJ10324
Human FLJ10324 (RADIL), RA domain
PDB: 3EC8 (2008-08-29)
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644. SERC
Human phosphoserine aminotransferase in complex with PLP
PDB: 3E77 (2008-08-18)
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633. TAT
Human tyrosine aminotransferase
PDB: 3DYD (2008-07-27)
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629. GMPS
Human guanine monophosphate synthetase
PDB: 2VXO (2008-07-08)
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619. DDX52
Human DEAD-box RNA-helicase DDX52, conserved domain I in complex with ADP
PDB: 3DKP (2008-06-25)
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616. DEADC1
Human tRNA-specific adenosine-34 deaminase subunit ADAT2
PDB: 3DH1 (2008-06-17)
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613. RRM2B
Human Ribonucleotide reductase, subunit M2 B
PDB: 2VUX (2008-05-31)
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602. FIGNL1
Human Fidgetin-like 1
PDB: 3D8B (2008-05-23)
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600. ALOX12
Human arachidonate 12-lipoxygenase
PDB: 3D3L (2008-05-12)
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594. GLS
Human glutaminase
PDB: 3CZD (2008-04-29)
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579. NUDT16
Human Nudix motif 16 (NUDT16)
PDB: 3COU (2008-03-29)
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575. CTH
Human Cystathionine Gamma-Lyase in complex with DL-propargylglycine
PDB: 3COG (2008-03-28)
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574. DHP
Human Dihydropyrimidinase
PDB: 2VR2 (2008-03-25)
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561. GMPS
Human guanine monophosphate synthetase - glutaminase domain
PDB: 2VPI (2008-02-29)
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PARP3
Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor PJ34
PDB: 3CE0 (2008-02-28)
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556. PTK2B
Human Protein Tyrosine Kinase 2 Beta
PDB: 3CC6 (2008-02-25)
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TULP1
Human TULP1 in complex with IP3
PDB: 3C5N (2008-01-31)
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PARP3
Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor KU0058948
PDB: 3C49 (2008-01-30)
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PARP3
Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor DR2313
PDB: 3C4H (2008-01-30)
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543. BCL2A1
Human Bcl2-A1 in complex with BIM-BH3 peptide
PDB: 2VM6 (2008-01-23)
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542. BIRC1
Human baculoviral inhibitor of apoptosis repeat-containing protein 1 (BIRC1), BIR2 domain
PDB: 2VM5 (2008-01-23)
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538. CTPS2
Human CTP synthetase 2 - glutaminase domain
PDB: 2VKT (2007-12-28)
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528. PARP15
Human Poly(ADP-Ribose) Polymerase15
PDB: 3BLJ (2007-12-11)
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527. EPB41L3
Human DAL-1 in complex with TSLC1
PDB: 3BIN (2007-11-30)
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519. THTPA
Human Thiamine Triphosphatase
PDB: 3BHD (2007-11-28)
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514. DDX47
Human DEAD-box RNA-helicase DDX47, conserved domain I in complex with AMP
PDB: 3BER (2007-11-20)
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505. ACOT12
Human Acyl-coenzyme A thioesterase 12
PDB: 3B7K (2007-10-31)
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DDX20
Human DEAD-box RNA helicase DDX20, conserved domain I in complex with AMPPNP
PDB: 3B7G (2007-10-31)
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500. MDA5
Human DECH-box RNA Helicase MDA5, DECH-domain
PDB: 3B6E (2007-10-29)
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497. ADSL
Human adenylosuccinate lyase in complex with its substrate N6-(1,2-Dicarboxyethyl)-AMP, and its products AMP and fumarate.
PDB: 2VD6 (2007-09-30)
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493. TNKS1
Human Tankyrase 1 - catalytic PARP-domain
PDB: 2RF5 (2007-09-28)
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481. STARD5
Human StAR-related lipid transfer protein 5
PDB: 2R55 (2007-09-03)
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475. GART
Human aminoimidazole ribonucleotide synthetase, AIRS domain
PDB: 2V9Y (2007-08-28)
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469. SPG7
Human Paraplegin, AAA domain in complex with ADP
PDB: 2QZ4 (2007-08-16)
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464. ACOT7
Human acyl-CoA thioesterase 7
PDB: 2QQ2 (2007-07-26)
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456. GART
Human glycinamide ribonucleotide synthetase, GARS domain
PDB: 2QK4 (2007-07-10)
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455. CSAD
Human Cysteine Sulfinic Acid Decarboxylase in complex with PLP
PDB: 2JIS (2007-06-30)
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441. ADSS2
Human Adenylosuccinate synthetase isozyme 2
PDB: 2V40 (2007-06-26)
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428. STARD13
Human START domain containing protein 13
PDB: 2PSO (2007-05-07)
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426. PARP12
Human Poly [ADP-ribose] polymerase 12
PDB: 2PQF (2007-05-02)
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420. GUAD
Human guanine deaminase
PDB: 2UZ9 (2007-04-26)
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409. DDX10
Human DEAD-box RNA Helicase DDX10, DEAD domain
PDB: 2PL3 (2007-04-19)
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400. PARP3
Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor 3-aminobenzoic acid
PDB: 3FHB (2007-03-27)
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393. DDX41
Human DEAD-box RNA Helicase DDX41, Helicase domain
PDB: 2P6N (2007-03-19)
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388. BIRC3
Human baculoviral inhibitor of apoptosis repeat containing protein 3 (BIRC3), BIR3 domain
PDB: 2UVL (2007-03-08)
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377. PRPSAP2
Human phosphoribosyl pyrophosphate synthetase - associated protein 41 (pap41)
PDB: 2JI4 (2007-02-25)
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375. DDX20
Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP
PDB: 2OXC (2007-02-20)
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374. UMPS
Human Uridine monophosphate synthetase - Orotidine-5'-decarboxylase domain
PDB: 2JGY (2007-02-16),
2V30 (2007-06-10)
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351. UCK1
Human Uridine-Cytidine Kinase 1
PDB: 2JEO (2007-01-18),
2UVQ (2007-03-13)
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350. GS
Human Glutamine Synthetase
PDB: 2OJW (2007-01-15),
2QC8 (2007-06-19)
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348. BAK1
Human BCL2 antagonist/killer 1
PDB: 2JCN (2006-12-27)
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347. ITPK1
Human Inositol 1,3,4-trisphosphate 5/6-kinase
PDB: 2ODT (2006-12-26)
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335. PRTFDC1
Human Phosphoribosyl transferase domain containing 1
PDB: 2JBH (2006-12-07)
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328. PPP2R5C
Human PP2A regulatory subunit B56g
PDB: 2JAK (2006-11-29)
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322. ASS
Human Argininosuccinate synthase
PDB: 2NZ2 (2006-11-22)
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312. CTH
Human Cystathionine gamma lyase
PDB: 2NMP (2006-10-23)
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310. ADSL
Human Adenylosuccinate Lyase in complex with AMP
PDB: 2J91 (2006-10-19)
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300. TLR10
The TIR domain of human Toll-Like Receptor 10 (TLR10)
PDB: 2J67 (2006-09-26)
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292. ALDRL6
Human Aldehyde reductase like 6
PDB: 2IBN (2006-09-11)
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278. DDX3X
Human DEAD-box RNA helicase DDX3X
PDB: 2I4I (2006-08-21)
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276. NT5C2
Human Purine 5-prime-nucleotidase
PDB: 2J2C (2006-08-16),
2JC9 (2006-12-21),
2JCM (2006-12-27)
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270. PHPT1
Human phosphohistidine phosphatase 1
PDB: 2HW4 (2006-07-31)
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260. RRM2
Human ribonucleotide reductase, R2 subunit
PDB: 2UW2 (2006-07-26)
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248. EPB41L3
FERM domain of EPB41L3 (DAL-1)
PDB: 2HE7 (2006-06-21)
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244. SCLY
Human selenocysteine lyase
PDB: 2HDY (2006-06-21)
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236. THEM2
Human thioesterase superfamily member 2
PDB: 2H4U (2006-05-25)
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234. NT5C3
Human Cytosolic 5'-nucleotidase
PDB: 2CN1 (2006-05-17),
2JGA (2007-02-09)
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219. DPYSL2
Human Dihydropyrmidineaselike 2
PDB: 2GSE (2006-04-26)
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215. CPSF5
Human Cleavage and Polyadenylation Specificity Factor 5
PDB: 2CL3 (2006-04-25),
2J8Q (2006-10-27)
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210. PIP5K2C
Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma
PDB: 2GK9 (2006-03-31)
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197. DDX2A/eIF4A
DEAD domain of human DEAD-box helicase 2 DDX2A
PDB: 2G9N (2006-03-07)
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190. PPP2R4
Human Protein Phosphatase 2A Regulatory Subunit PPP2R4
PDB: 2G62 (2006-02-24)
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FTHFD + 6-formylpteridin
Human 10-FTHFD in complex with 6- formylpteridin, hydrolase domain
PDB: 2CFI (2006-02-21)
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187. DDX25
Human DEAD-box RNA helicase DDX25, Helicase domain
PDB: 2RB4 (2006-02-16)
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180. IMPA2
Human inositol monophosphatase
PDB: 2FVZ (2006-01-31)
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179. NUDT3 (DIPP1)
Human Diphosphoinositol polyphosphate phosphohydrolase
PDB: 2FVV (2006-01-31),
2Q9P (2007-06-13)
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167. TULP1
Human Tubby-like protein 1, C-terminal domain
PDB: 2FIM (2005-12-29)
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166. ITPA
Human Inosine Triphosphatase
PDB: 2CAR (2005-12-22)
2J4E (2006-08-29)
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152. FABP1
Human Fatty acid binding protein 1, liver
PDB: 2F73 (2005-11-30)
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143. GMPR2-NADPH/IMP
Human Guanosine monophosphate reductase 2 in complex with NADPH/IMP
PDB: 2C6Q (2005-11-11)
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138. CTPS
Human CTP Synthetase - Synthetase Domain
PDB: 2c5m (2005-10-28)
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131. PRPSAP1
Human phosphoribosylpyrophosphate synthetase-associated protein 1
2C4K (2005-10-20)
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101. GMPR2
Human Guanosine monophosphate reductase 2 [isoform 1]
PDB: 2BZN (2005-08-19)
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83. ITPKC
Catalytic Domain of Human Inositol 1,4,5- Trisphosphate 3-Kinase C
PDB: 2A98 (2005-07-11)
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82. FTHFD
Human 10-Formyltetrahydrofolate Dehydrogenase - Hydrolase Domain
PDB: 2BW0 (2005-07-08)
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